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dissociation one phase exponential decay algorithm prism10.2.1  (GraphPad Software Inc)


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    GraphPad Software Inc dissociation one phase exponential decay algorithm prism10.2.1
    Dissociation One Phase Exponential Decay Algorithm Prism10.2.1, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dissociation%E2%80%9Cone-phase+exponential+decay+algorithm/prism+10/pm39937529-524-13-14
    Average 90 stars, based on 1 article reviews
    dissociation one phase exponential decay algorithm prism10.2.1 - by Bioz Stars, 2026-09
    90/100 stars

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    Article Snippet: Fluorescently labeled ligands are versatile molecular tools to study G protein-coupled receptors (GPCRs) and can be used for a range of different applications, including bioluminescence resonance energy transfer (BRET) assays.. Here, we report the structure-based development of fluorescent ligands targeting the intracellular allosteric binding site (IABS) of the CC chemokine receptor 2 (CCR2), a class A GPCR that has been pursued as a drug target in oncology and inflammation.. Starting from previously reported intracellular CCR2 antagonists, several tetramethylrhodamine (TAMRA)-labeled CCR2 ligands were designed, synthesized, and tested for their suitability as fluorescent reporters to probe binding to the IABS of CCR2.



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